Kidney Stone Research

Management of ureteral calculi and medical expulsive therapy inemergency departments

Management of ureteral calculi and medical expulsive therapy inemergency departments

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MET should be offered as a treatment for patients with distal ureteral calculi who are amenable to awaiting management. Benefits associated with MET are a shorter time to stone expulsion and less need for analgesic drugs and hospitalization for treatment. MET is cost effective for the management of distal ureteral stones.
Guideline of guidelines for kidney and bladder stones

Guideline of guidelines for kidney and bladder stones

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 both AUA and EAU guidelines offer a detailed, evidence-based framework to guide the urologists in the management of stone diseases. Although some discrepancies exist, particularly regarding the choice of surgical management in specific scenarios, there is generally a consensus between both the groups. However, the guidelines are not applicable to every clinical situation and need to be used in conjunction with the most recently published material and tailored to each individual patient.
Medical expulsive treatment in pediatric urolithiasis

Medical expulsive treatment in pediatric urolithiasis

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The frequency of stone disease in childhood ranges between 0.1-5 percent. Stone disease occurs as a result of enviromental, metabolic, anatomical, infectious and nutritional factors. Percutaneous nephrolitotomy, uretherorenoscopy, laparoscopic surgery, open surgery and extracorporeal shock wave lithothripsy are treatment alternatives for stone disease during childhood. However, these methods are not completely innocent. Some complications may occur after these procedures. These procedures are generally not cost- effective. Even invasive procedures have high success rates, so medical expulsive treatment modalities have become an alternative for a group of patients.
The Use of Alpha-Blockers for the Treatment of Nephrolithiasis

The Use of Alpha-Blockers for the Treatment of Nephrolithiasis

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Alpha blockers may also be a useful adjunct in the treatment of both ureteral and renal stones with SWL. They may also reduce the urinary symptoms and pain associated with double-J ureteral stents. Further investigation is necessary to define the role of  blockers in the treatment of proximal ureteral and renal stones, and to elucidate the potential mechanisms of renal stone clearance after surgical stone intervention.
Medical expulsive therapy for ureteric stones: Analysing the evidence from systematic reviews and meta-analysis of powered double-blinded randomised controlled trials

Medical expulsive therapy for ureteric stones: Analysing the evidence from systematic reviews and meta-analysis of powered double-blinded randomised controlled trials

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The primary findings show a small overall benefit for a-blockers as MET for ureteric stones but no benefit with CCBs. a-blockers show a greater benefit for large (>5 mm) ureteric stones and those located in the distal ureter, but no benefit for smaller or more proximal stones. a-blockers are associated with a greater risk of side-effects compared to placebo or CCBs. 2017 Production and hosting by Elsevier B.V. on behalf of Arab Association of Urology. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
Medical expulsive therapy

Medical expulsive therapy

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The AUA/EAU guidelines suggest MET as a reasonable treatment choice in select patients. Previous studies have demonstrated a significant benefit in stone expulsion rates with the use of MET. A review of the data suggests greater success rates occur with the use of alpha antagonist compared to calcium channel blockers. The use of MET is not limited to just those patients attempting passage of calculi without other interventions; there is also an advantage to MET in those subjects treated with other modalities (i.e. SWL and ureteroscopy).
Even with multiple studies demonstrating the benefits of MET, it still is underutilized as a treatment modality. Education in the hospital setting appears to be beneficial in changing practice behaviors. MET may reduce medical costs and prevent unnecessary surgeries and the associated risks.
Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka

Outcome of uncomplicated ureteric calculi managed with medical expulsive therapy in the outpatient clinic of a urology unit in Sri Lanka

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Only a minority of patients with ureteric calculi require surgical intervention. Uncomplicated ureteric stones up to 10 mm can be given a trial of MET initially. The trial period may be extended up to 12-weeks depending on the control of symptoms and downward movement of the stone.
Extracorporeal shockwave lithotripsy monotherapy for treating patients with bladder stones

Extracorporeal shockwave lithotripsy monotherapy for treating patients with bladder stones

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ESWL monotherapy is safe and effective method for treatment of bladder stones with no other causes of infra-vesical obstruction. Several indications can be met including patients with high anaesthetic risk, patients fearing anaesthesia or endoscopic procedures, and patients who have difficulty in positioning. 2016 Arab Association of Urology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/)
Association between time to lithotripsy and stone‑free rate in patients with ureteral stones undergoing shock wave lithotripsy

Association between time to lithotripsy and stone‑free rate in patients with ureteral stones undergoing shock wave lithotripsy

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Time to lithotripsy is strongly associated with SFR following SWL. SWL in an urgent care setting does not improve SFR if it is performed within 1 month, while time to SWL > 2 months reduces the likelihood of stone-free status.
How can and should we optimize extracorporeal shockwave lithotripsy?

How can and should we optimize extracorporeal shockwave lithotripsy?

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The purpose of this article is to emphasize some important aspects on how SWL best should be used. Based on decades of experience, it stands to reason that success with SWL does not come automatically and attention has to be paid to all details of this technique.
Postoperative infective complications following percutaneous nephrolithotomy

Postoperative infective complications following percutaneous nephrolithotomy

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Post‑PCNL complications are more commonly found in patients with history of preoperative UTI, previous history of renal surgeries, large stone burden, operative procedure more than 90 min, and presence of residual calculi.
Study of predictive factors affecting the prolonged urinary leakage after percutaneous nephrolithotomy

Study of predictive factors affecting the prolonged urinary leakage after percutaneous nephrolithotomy

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In the present study, several factors appear to affect post‑PCNL prolonged urinary leakage. We suggest that patients who are at increased risk of prolonged urinary leakage double‑J stent should be placed at the end of PCNL procedure.

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