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Kidney Stone Research

The Use of Alpha-Blockers for the Treatment of Nephrolithiasis

The Use of Alpha-Blockers for the Treatment of Nephrolithiasis

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by Arshad Ali
Alpha blockers may also be a useful adjunct in the treatment of both ureteral and renal stones with SWL. They may also reduce the urinary symptoms and pain associated with double-J ureteral stents. Further investigation is necessary to define the role of  blockers in the treatment of proximal ureteral and renal stones, and to elucidate the potential mechanisms of renal stone clearance after surgical stone intervention.
alpha α Blockers Alpha-blockers kidney stone Kidney stones Passing a Kidney Stone stone treatment Treatment Options Treatment strategies ureteral stones
Medical expulsive therapy

Medical expulsive therapy

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by Arshad Ali
The AUA/EAU guidelines suggest MET as a reasonable treatment choice in select patients. Previous studies have demonstrated a significant benefit in stone expulsion rates with the use of MET. A review of the data suggests greater success rates occur with the use of alpha antagonist compared to calcium channel blockers. The use of MET is not limited to just those patients attempting passage of calculi without other interventions; there is also an advantage to MET in those subjects treated with other modalities (i.e. SWL and ureteroscopy).
Even with multiple studies demonstrating the benefits of MET, it still is underutilized as a treatment modality. Education in the hospital setting appears to be beneficial in changing practice behaviors. MET may reduce medical costs and prevent unnecessary surgeries and the associated risks.
Expulsive Therapy How Kidney Stones Form Kidney stones Medical expulsive therapy Preventing Kidney Stones ureteral stones Urolithiasis
How can and should we optimize extracorporeal shockwave lithotripsy?

How can and should we optimize extracorporeal shockwave lithotripsy?

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by Arshad Ali
The purpose of this article is to emphasize some important aspects on how SWL best should be used. Based on decades of experience, it stands to reason that success with SWL does not come automatically and attention has to be paid to all details of this technique.
Extracorporeal shockwave lithotripsy How Kidney Stones Form kidney Kidney Calculi Kidney stones Lithotripsy Passing a Kidney Stone Precautions Renal stones Treatment strategies ureteral stones
Optical puncture combined with balloon dilation PCNL vs. conventional puncture dilation PCNL for kidney stones without hydronephrosis: a retrospective study

Optical puncture combined with balloon dilation PCNL vs. conventional puncture dilation PCNL for kidney stones without hydronephrosis: a retrospective study

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by Arshad Ali
Optical puncture combined with balloon dilation PCNL could be associated with good therapeutic effect and low frequency of complications for the treatment of kidney stones without hydronephrosis.
Balloon dilation Endoscopes impacted stones Kidney Calculi Kidney Stone Types Kidney stones Kidney stones without hydronephrosis Lithotripsy Nephrolithotomy Optical puncture PCNL Percutaneous Nephrolithotomy (PCNL) ureteral stones ureteric stone
Retrograde intrarenal surgery for lower pole renal calculi smaller than one centimeter

Retrograde intrarenal surgery for lower pole renal calculi smaller than one centimeter

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by Arshad Ali

RIRS continues to undergo signiÞ cant advancements and is emerging as a Þ rst-line procedure for challenging stone cases. The treatment of choice for LC calculi < 1 cm depends on patient’s preference and the individual surgeon’s preference and level of expertise.

flexible ureteroscopy holmium laser lithotripsy kidney stone lower calyx Lower urinary tract symptoms renal calculi Renal stone Retrograde intrarenal surgery Upper urinary calculi ureteral stones
Effect of perioperative selective alpha-1 blockers in non-stented ureteroscopic laser lithotripsy for ureteric stones: a randomized controlled trial

Effect of perioperative selective alpha-1 blockers in non-stented ureteroscopic laser lithotripsy for ureteric stones: a randomized controlled trial

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by Arshad Ali

Administration of perioperative Flo-max seems to not only to significantly decrease the need for intra-operative dilatation and hence operative time, but also leads to a significant decrease in the development of postoperative LUTs, postoperative pain and the need for analgesia and hospital stay.

Alpha-1 blocker Kidney stones Lower urinary tract symptoms Non-stented Postoperative pain Treatment Options ureteral stones Ureteroscopic lithotripsy
Retrograde versus Antegrade Approach for the Management of Large Proximal Ureteral Stones

Retrograde versus Antegrade Approach for the Management of Large Proximal Ureteral Stones

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by Arshad Ali
Antegrade ureteroscopy is an efficient and safe option for the management of large proximal ureteral stones. It may achieve high stone-free rates compared to retrograde ureteroscopy with the drawback of longer operative time, fluoroscopy time, and length of hospitalization.
Antegrade ureteroscopy Kidney stones Renal stone Treatment Options ureteral stones Ureteroscopy

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